Congratulations to our champion postdoctoral researcher, Blagojce Jovcevski, for his success in gaining a fellowship from the Hospital Research Foundation Group!
Blagojce’s research will look at protein function in the gut and will focus on Parkinson’s and MND.
Issues with protein quality control leads to Lewy body morphologies in Parkinson’s disease. Previous work in this area has focused on protein quality control in the brain as the region of disease onset however, recent evidence suggests that initial seeding events occur presymptomatically in the gut-brain axis prior to deposition in the brain. This fellowship will investigate these protein quality control mechanisms that fail in the gut-brain axis causing diseases namely Parkinson’s disease and motor neuron disease. The project will help us better understand how these diseases originate and progress, inform new biomarkers for diagnosis and guide treatment strategies.